Highly purified. Control Peptide for A3000-75 (antiserum) and A3000-80 (affinity purified) A 17aa synthetic peptide within the cytoplasmic, C-terminal region of human AQP10. Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporin. Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. A new member of AQP family, AQP10, has been cloned (1). AQP10 (human 264 aa) is most closely related with AQP3 (53%), AQP9 (52%), and AQP7 (43%). It is abundantly expressed in duodenum and jejunum. AQP10 is not permeable to urea and glycerol. Applications: Suitable for use in EL