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Description
Mouse Anti-GFI1 Recombinant Antibody (CBLG1-074). This product is antibody recognizes GFI1. The antibody CBLG1-074 immunoassay techniques such as: ELISA, ICC, IHC, WB. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias a