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Description
PE anti-mouse DcTRAIL-R1. Mouse Decoy Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Receptor 1 (mDcTRAIL R1) is a GPI-anchored mouse TNF receptor super-family member that lacks a cytoplasmic death domain. It expresses on many cell types, including some tumor cells. mDcTRAIL R1 appears to have a negative effect against TRAIL receptors because it lacks an intracellular death domain, and produces a competitive blockage of TRAIL-mediated apoptosis. The role of the DcR1 in apoptosis has not yet been clarified.
Immunogen
mDcTRAIL-R1-Fc
Other Names
TNFRH1, mSOB, Tumor necrosis factor receptor superfamily member 23, Tnfrsf23, Tumor necrosis factor receptor p60 homolog 1, TNF receptor family member SOB, Decoy TRAIL receptor 1, TNF receptor homolog 1