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Description
Mouse Anti-RASD2 Recombinant Antibody (1H10). This product is a Mouse antibody that recognizes RASD2. The antibody 1H10 can be used for immunoassay techniques such as: WB, IF, FC. This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this ge
Immunogen
Full length human recombinant protein of human RASD2 (NP_055125) produced in HEK293T cell
Other Names
RASD Family Member 2; Ras Homolog Enriched In Striatum; Tumor Endothelial Marker 2; TEM2; GTP-Binding Protein Rhes; RASD Family, Member 2; MGC:4834; Rhes;