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Description
Rabbit IgG polyclonal Picoband? antibody for Aldose reductase(AKR1B1) detection. Tested with WB, IHC-P IHC-F, ICC, FCM in Human;Mouse;Rat. No cross reactivity with other proteins. Aldo-keto reductase family 1, member B1 (aldose reductase), also known as AR, is an enzyme that in humans is encoded by the AKR1B1 gene. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number ofaldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
Immunogen
E. coli-derived human AKR1B1 recombinant protein (Position: L228-F316). Human AKR1B1 shares 87.5% amino acid (aa) sequence identity with both mouse and rat AKR1B1.
Other Names
Aldose reductase;AR;1.1.1.21;Aldehyde reductase;Aldo-keto reductase family 1 member B1;AKR1B1;ALDR1;