If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Mouse Anti-TRDN Recombinant Antibody (CBYJT-4590). Provided herein is a Mouse monoclonal antibody, which binds to TRDN (Triadin). The antibody can be used for immunoassay techniques, such as BL, ELISA, ICC, IF, IHC, IHC-Fr, IP, WB. TRDN contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction (PubMed:19398037, PubMed:17846166 and PubMed:7721813). TRDN is required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. It is required for normal skeletal muscle strength. TRDN plays a role in excitation-contraction coupling in the heart