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Description
Mouse Anti-KIT Recombinant Antibody (2B12). This product is antibody recognizes KIT. The antibody 2B12 immunoassay techniques such as: IHC, WB. This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Human recombinant protein fragment corresponding to amino acids 27-308 of human KIT(NP_000213) produced in E.coli