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Description
Rat Anti-FZD7 (Extracellular domain) Recombinant Antibody (CBXF-0994). This product is a rat antibody that recognizes FZD7 (Extracellular domain). The antibody CBXF-0994 can be used for immunoassay techniques such as: ELISA, WB. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinom
Immunogen
n/a
Other Names
Frizzled Class Receptor 7; Frizzled 7, Seven Transmembrane Spanning Receptor; Frizzled Family Receptor 7; Fz-7; FzE3; HFz7;