A Cdk1 inhibitor (IC50 = 20 μg/ml in PC-14 cells); induces dose-dependent G2/M arrest, inhibits DNA synthesis, and decreases Cdk1 protein expression in vitro; has antitumor effects in non-small lung, small cell lung, and prostate cancer cell lines (average IC50 = 50 μg/ml); inhibits in vitro Cdk1 phosphorylation of tau; inhibits in vivo phosphorylation of transcription factor E2F-1; increases biogenesis of the secondary metabolite lovastatin and conidiation in A. terreus,