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Description
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Purified His-tagged BAIAP2 protein was used to produced this monoclonal antibody.
Immunogen
Human BAIAP2.
Other Names
BAIAP2; Brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; Insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; BAP2; FLAF3; IRSP53; BAI-associated protein 2; BAI1-associated protein 2; Protein BAP2; IRS-58; IRSp53/58; Insulin receptor substrate p53