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Description
Mouse Anti-TK1 Recombinant Antibody (CBYJT-3264). Provided herein is a Mouse monoclonal antibody, which binds to TK1 (Thymidine Kinase 1). The antibody can be used for immunoassay techniques, such as ELISA, WB. TK1 is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. TK1, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers.
Immunogen
TK1 (AAH07986.1, 1aa-234aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD