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Description
Rabbit Anti-PTEN (Acetylated K402) Polyclonal Antibody (PTM-CBPAB-0966YC). Provided herein is a Rabbit polyclonal antibody against Phosphatase and Tensin Homolog. The antibody can be used for immunoassay techniques, such as ELISA, WB. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphati
Immunogen
Synthetic peptide corresponding to the human PTEN around the acetylation site of K402