human, rat (predicted: bovine, canine, hamster, horse, monkey, rabbit)
Isotype
n/a
Format
immunogen affinity purified
Size
100ug (sample available)
Concentration
500ug/ml.
Applications
WB
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Description
Rabbit IgG polyclonal Picoband? antibody for Polycomb protein EED(EED) detection. Tested with WB in Human;Rat.. No cross reactivity with other proteins. Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. Furthermore, this protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Immunogen
E.coli-derived human EED recombinant protein (Position: M256-R441). Human EED shares 100% amino acid (aa) sequence identity with mouse EED.
Other Names
Polycomb protein EED;hEED;WD protein associating with integrin cytoplasmic tails 1;WAIT-1;EED;