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Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq]. This MRPS23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-76 amino acids from the Central region of human MRPS23.
Immunogen
Human MRPS23.
Other Names
CGI-138; HSPC329; MRP-S23; MRPS23; 28S ribosomal protein S23; mitochondrial