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Description
Rabbit Anti-TNFRSF1B Recombinant Antibody (CBYJT-3822). Provided herein is a Rabbit monoclonal antibody, which binds to TNFRSF1B (TNF Receptor Superfamily Member 1B). The antibody can be used for immunoassay techniques, such as WB, IP, IHC-P, ICC, FC. TNFRSF1B is a member of the TNF-receptor superfamily. TNFRSF1B and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also sug
Immunogen
Synthetic peptide within Human TNF Receptor II aa 400 to the C-terminus (C terminal). The exact sequence is proprietary.
Other Names
TNF Receptor Superfamily Member 1B; Tumor Necrosis Factor Receptor Type II; Tumor Necrosis Factor Receptor 2; P80 TNF-Alpha Receptor; TNF-RII; TNF-R2; TNFR2; TNFBR; P75; Tumor Necrosis Factor Receptor Superfamily, Member 1B; Tumor Necrosis Factor Receptor Superfamily Member 1B; Tumor Necrosis Factor Binding Protein 2; Tumor Necrosis Factor Beta Receptor