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Description
Mouse Anti-TNFRSF10C Recombinant Antibody (CBYJT-3666). Provided herein is a Mouse monoclonal antibody, which binds to TNFRSF10C (TNF Receptor Superfamily Member 10c). The antibody can be used for immunoassay techniques, such as FC, CyTOF. TNFRSF10C is a member of the TNF-receptor superfamily. It contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. It is not capable of inducing apoptosis, and is thought to play a role as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. TNFRSF10C was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the speci
Immunogen
Mouse myeloma cell line NS0-derived recombinant human TRAIL R3/TNFRSF10C, Met1-Ala221, Accession # O14798
Other Names
TNF Receptor Superfamily Member 10c; Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain; TNF-Related Apoptosis-Inducing Ligand Receptor 3; Antagonist Decoy Receptor For TRAIL/Apo-2L; Decoy TRAIL Receptor Without Death Domain; Lymphocyte Inhibitor Of TRAIL; Decoy Receptor 1; TRAIL-R3; TRAILR3; DCR1