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Description
Mouse Anti-TNFRSF13C Recombinant Antibody (8A7). This product is antibody recognizes TNFRSF13C. The antibody 8A7 immunoassay techniques such as: FC, IHC-F, WB. B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing
Immunogen
n/a
Other Names
TNF Receptor Superfamily Member 13C; BLyS Receptor 3; BAFF Receptor; BAFF-R; BAFFR; Tumor Necrosis Factor Receptor Superfamily, Member 13C; Tumor Necrosis Factor Receptor Superfamily Member 13C; B Cell-Activating Factor Receptor;