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Description
Mouse Anti-USP13 Recombinant Antibody (5B9). This product is a mouse antibody that recognizes USP13. The antibody 5B9 can be used for immunoassay techniques such as: IP, WB. Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD). Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the exi
Immunogen
Full-length protein expressed in 293T cell transfected with human USP13 expression vector