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Description
SCP3 Polyclonal Antibody, Cy7 Conjugated. ? Target Background: Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
Immunogen
KLH conjugated synthetic peptide derived from human SCP3. Immunogen Range: 150-200/276
Other Names
PSR1; SCP3; HYA22; RBSP3; C3orf8; CTD small phosphatase-like protein; CTDSP-like; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; NIF-like protein; Nuclear LIM interactor-interacting factor 1; NLI-interacting factor 1; Protein YA22; Small C-terminal domain phosphatase 3; Small CTD phosphatase 3; CTDSPL; NIF1; NIFL; YA22