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Description
c-Raf(Thr269) Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: The Raf family of serine/threonine specific kinases is comprised of three members (aRaf, bRaf, and cRaf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen activated protein kinase (MAPK) pathway. cRaf kinase (also known as Raf1) is a small GTPase like kinase of 73 kDa, and is a signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that
Immunogen
KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Thr269