Recombinant Human Heat shock protein HSP 90-alpha (HSP90AA1), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 27.2kDa. Partial: 9-232aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Heat shock 86KDA; HSP 86; HSP86Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2Renal carcinoma antigen NY-REN-38