An inhibitor of staphylococcal FabI (Ki = 12.8 nM); selective for isolates of methicillin-susceptible and methicillin-resistant S. aureus (MIC90s = ≤0.008 μg/ml) over isolates of S. pneumoniae, β-hemolytic streptococci, Enterococcus, Enterobacteriaceae, non-fermentative Gram-negative bacilli, and M. catarrhalis (MIC90s = >4 μg/ml); increases survival in a murine acute lethal septicemia model at 1 mg/kg