Purity ~95% (SDS-PAGE). IL1R1, also known as interleukin-1 receptor type 1, associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. It is an important mediator involved in many cytokine induced immune and inflammatory responses. Source: Recombinant protein corresponding to aa21-336 from human IL1R1, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~37.4kD(324aa) AA