Purity ~98% (SDS-PAGE). Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function. Source: Recombinant protein corresponding to aa19-328 from human IL-33R, fused to the N-terminus of the Fc region, expressed in CHO cells. Biological Activity: Measured by its ability to bind recombinant human IL-33 in a functional ELISA. Endotoxin: ~0.06EU/ug protein (LAL test; Lonza)