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Description
Purified anti-PKC. PKC, also known as protein kinase C, belongs to a kinase family involved in intracellular signaling processes. PKC isoforms are divided into three groups known as conventional (including PKCα, PKCβ1, PKCβ2 and PKCγ), novel (including PKCε, μ, θ, δ, η), and atypical PKC isoforms (such as ξ). Conventional PKC isoforms require calcium and diacylglycerol for activation, novel isoforms require diacylglycerol, and atypical isoforms require neither calcium nor diacylglycerol. Once activated by phosphorylation, the PKCs phosphorylate a large variety of substrates involved in cell differentiation, proliferation, and activation. The PKC0103 antibody recognizes human, mouse, and rat PKC and is useful for Western blotting and immunoprecipitation.