Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) (aa 250-300)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human
Isotype
n/a
Format
serum
Size
100 μL
Concentration
n/a
Applications
Immunohistochemistry (IHC),Western Blotting (WB)
Reviews / Ratings
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Description
FUNCTION: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs). SUBCELLULAR LOCATION: Basolateral cell membrane, Multi-pass membrane protein. Apical cell membrane, Multi-pass membrane protein. Note: Predominantly localized in the basolateral membrane in polarized MDCK cells. Tissue specificity: Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen. Synonyms: Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, ENT1
Immunogen
A synthetic peptide from aa region 250-300 of human SLC29A1 conjugated to an immunogenic carrier protein was used as the antigen.