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Description
VAV1 (Tyr174) Polyclonal Antibody. ? Target Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiate
Immunogen
KLH conjugated synthetic phosphopeptide derived from human VAV1 around the phosphorylation site of Tyr174