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Description
Mouse Anti-KRT8 Recombinant Antibody (8G8). This product is antibody recognizes KRT8. The antibody 8G8 immunoassay techniques such as: IHC. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for
Immunogen
The CK8 Mouse Monoclonal antibody detects endogenous CK8 proteins (~54KD)