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Description
Rabbit Anti-ATM (Phosphorylated S1981) Recombinant Antibody (PTM018YC). Provided herein is a Rabbit monoclonal antibody against ATM Serine/Threonine Kinase. The antibody can be used for immunoassay techniques, such as ICC, IF, IHC, IHC-P, IP, WB. ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response t
Immunogen
A synthetic peptide corresponding to residues surrounding serine 1981 of human ATM.
Other Names
ATM Serine/Threonine Kinase; Ataxia Telangiectasia Mutated; A-T Mutated; EC 2.7.11.1; Ataxia Telangiectasia Mutated (Includes Complementation Groups A, C And D); TEL1, Telomere Maintenance 1, Homolog (S. Cerevisiae); TEL1, Telomere Maintenance 1, Homolog; Serine-Protein Kinase ATM; AT Mutated;