Purity ~90% (SDS-PAGE). Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. Source: Recombinant protein corresponding to aa5-514 from human IMPD2, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~82.3kD AA