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Description
Rabbit Anti-ARRB1 (Phosphorylated S412) Polyclonal Antibody (PTM-CBPAB-0294YC). Provided herein is a Rabbit polyclonal antibody against Arrestin Beta 1. The antibody can be used for immunoassay techniques, such as WB. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus