This phosphotyrosil peptide sequence is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). Using synthetic pTyr-containing peptides that correspond to natural phosphorylation sites in proteins, several groups have demonstrated that PTPases display a range of kcat/Km values for these relatively short peptide substrates. This peptide is a minimal (6 residues) peptide substrate for both the Yersinia PTPase and the mammalian PTP1. It is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B).
Size
0.5 mg
Concentration
n/a
Applications
n/a
Other Names
C-erb|CG10079|D-EGFR|D-Egf|DEGFR|DER|DER flb|DER/EGFR|DER/faint little ball|DER/top|DER/torpedo|DER1|DEgfr|Degfr|Der|DmHD-33|Dmel\\CG10079|EFG-R|EGF-R|EGFR|EGFr|EGfr|EK2-6|Egf|Egf-r|EgfR|El|Elp|Elp-1|Elp-B1|Elp-B1RB1|HD-33|TOP|Torpedo/DER|Torpedo/Egfr|c-erbB|d-egf-r|dEGFR|dEGFR1|dEgfr|der|egfr|flb|l(2)05351|l(2)09261|l(2)57DEFa|l(2)57EFa|l(2)57Ea|mor1|top|top/DER|top/flb|torpedo/Egfr|torpedo/egfr|EGFR12|EGFR15|egfr1|Erbb2|ERBB|ERBB1|HER1|PIG61|mENA|ErbB-1|Errp|9030024J15Rik|AI552599|Erbb|Errb1|Wa5|wa-2|wa2