Heat Shock Protein HSP 90-alpha, Recombinant, Porcine, aa222-367, His-Tag (HSP90AA1)
Description
Purity ~90% (SDS-PAGE). Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion (By similarity). Source: Recombinant protein corresponding to aa222-367 from porcine Heat shock protein HSP 90-alpha, fused to His-Tag at N-terminal, expressed in Baculovirus. Molecular Weight: ~19.7kD AA