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| Antigenic Specificity | KLHL12 |
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| Clone | 1E6 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-KLHL12 Recombinant Antibody (1E6). This product is antibody recognizes KLHL12. The antibody 1E6 immunoassay techniques such as: WB. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by Ref |
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| Immunogen | Human recombinant protein fragment corresponding to amino acids 177-405 of human KLHL12 (NP_067646) produced in E.coli |
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| Other Names | Kelch Like Family Member 12; CUL3-Interacting Protein 1; DKIR Homolog; C3IP1; Kelch-Like 12 (Drosophila); Kelch-Like Protein C3IP1; Kelch-Like Protein 12; HDKIR; DKIR; |
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| Gene, Accession # | Gene ID: 59349 |
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| Catalog # | CBMAB-K1175-LY |
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| Price | |
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| Order / More Info | KLHL12 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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