Purity ~90% (SDS-PAGE). Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division. Source: Recombinant protein corresponding to aa1-354 from human GNAI3, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~44.5kD AA