The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. Recombinant human MIF was expressed in E. coli and purified by conventional chromatography techniques. Alternative Names: Clo protein, MMIF protein, Stem cell factor protein, Steel protein, contrasted protein, Mgf protein, Kitlg protein, Sl protein, glycosylation inhibiting factor (GIF) protein, Gb protein, Con protein, Kitl protein, GLIF protein, Stem cell factor, SCF protein, SLF protein, mouse SCF protein, SF protein