Purified (SDS-PAGE). Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin beta1 and beta 3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage- independent cell cycle progression, tumor cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies. Source: Recombinant corresponding to aa1-452 from mature human full-length ILK1, fused to 6x His-tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot as a control.
Size
10ug
Concentration
n/a
Applications
WB
Other Names
ILK, Recombinant, Human, Western Blot Control (Integrin Linked Kinase, Integrin-linked Protein Kinase, 59kD Serine/threonine Protein Kinase, DKFZp686F1765, ILK 1, ILK1, ILK-1, ILK 2, ILK2, ILK-2, p59, p59ILK)