Purity ~98% (SDS-PAGE and HPLC). MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant murine MIP-3 beta is a 9.2kD protein containing 83aa, including the four highly conserved cysteine residues present in CC chemokines. Source: Recombinant protein corresponding to mouse MIP-3 beta, expressed in E.coli. Biological Activity: Determined by its ability to chemoattract human mature dendritic cells using a concentration range of 10-100ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS