Purity ~98% (SDS-PAGE and HPLC). Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78aa (92aa residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3kD protein containing 93aa. Source: Recombinant protein corresponding to mouse Eotaxin-2, expressed in E.coli. Biological Activity: Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV