Ketanserin Tartrate (5-HT2A Serotonin Receptor Antagonist, Ketanserin, R 41 468)
Description
Purity ~97% (HPLC). A selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking properties. Strong affinity for 5-HT2AR (Ki = 1.49nM) relative to other family members like 5-HT2BR (Ki = 740nM) and 5-HT2CR (Ki = 59nM). Often used in conjunction with SB 206553 to distinguish 5-HT2AR and 5-HT2CR activity. Solubility: DMSO Primary Target: 5-HT2A Primary Target Ki: 1.49nM