Purity ~90% (SDS-PAGE). KDR, also known as vascular endothelial growth factor receptor 2, is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR (1, 2 and 3). VEGFR2 was shown to be the primary signal transducer for angiogenesis and the development of pathological conditions like cancer. Also, this protein is expressed mainly in the endothelial cells, and the expression is upregulated in the tumor vasculature. Source: Recombinant protein corresponding to aa20-764 from human KDR protein, fused to hIgG-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~110.5kD (987aa), 100-150kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) AA