Purified (SDS-PAGE). Tissue polypeptide specific antigen was first identified as a tumor marker in the late 1950's, but has recently been shown to be closely related to human cytokeratin 18. Cytokeratins are a group of about 20 cytoskeletal proteins, whose degradation gives rise to soluble fragments, measurable in the blood of patients. Serum levels are high in breast cancer patients and also some other malignancies, probably due to high cell turnover in tumors. Source: Recombinant corresponding to human CK-18, fused to 6x His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~51.6kD Applications: Suitable for use in Western Blot as a control.
Size
10ug
Concentration
n/a
Applications
WB
Other Names
KRT18, Recombinant, Human, Western Blot Control (Keratin, Type I Cytoskeletal 18, Cytokeratin-18, CK-18, Keratin-18, K18, Cell Proliferation-inducing Gene 46 Protein, PIG46, CYK18)