CTGFL/WISP-2 is a 28.6 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.
Size
Various Sizes
Concentration
n/a
Applications
Cell Culture
Other Names
WNT1-inducible-signaling pathway protein 2;WISP-2;CCN family member 5;Connective tissue growth factor-like protein;CTGF-L;Connective tissue growth factor-related protein 58;WISP2;CCN5, CT58, CTGFL;UNQ228/PRO261; Connective Tissue Growth Factor-Like protein, CCN5, CT-58