Angiopoietin-related protein 4 (Angptl4) is a protein that in humans is encoded by the ANGPTL4 gene. This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. By radiation hybrid analysis, Angptl4 gene is mapped to 19p13.3. ANGPTL4 contributed to tumor growth and protected cells from anoikis, a form of programmed cell death induced when contact-dependent cells detach from the surrounding tissue matrix. Intended Use: ANGPTL4 BioAssay? ELISA Kit is a sandwich ELISA for quantitative detection of human ANGPTL4 in cell culture supernates, serum and plasma (heparin, EDTA, citrate). Assay Range: 625pg/ml-40,000pg/ml Sensitivity: <20 pg/ml Crossreactivity: There is no detectable cross-reactivity with other relevant proteins. Kit Components: 143718A: Microtiter Strips, 1x