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Description
HDAC1/2 (Ser423/424) Polyclonal Antibody, Alexa Fluor? 647 Conjugated. ? Target Background: Reversible acetylation of highly conserved lysine residues within the N-terminal tail domains of core histones, plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone acetylation is a dynamic process determined by the net activities of histone acetyltransferases (HATs) and the competing enzymes histone deacetylases (HDACs). Histone deacetylases activities are often, but not always, associated with transcriptional repression and nucleosomal
Immunogen
KLH conjugated synthetic phosphopeptide derived from human HDAC1 around phosphorylation site of Ser423