A 5-HT3 receptor antagonist (Ki = 995 nM and IC50 = 308 nM in rat cortical membranes); D2 receptor antagonist (IC50 = 483 nM in rat brain synaptic membranes); oral administration inhibits cisplatin-induced emesis in ferrets and apomorphine-induced emesis in dogs (ED50s = 6.170 and 0.45 mg/kg, respectively); reversibly inhibits human AChE isolated from caudate nucleus (Kis = 9.3 and 82 μM for competitive and non-competitive inhibition, respectively)