Purity ~98% (HPLC). A potent inhibitor of dopamine active transporter (DAT, Ki = 1nM, IC50 = 40 and 51nM) with >100 fold selectivity over noradrenalin and 5-HT re-uptake transporter. Shown to produce behavioral profile in mice for bipolar mania disease model and ADHD disease models. Solubility: DMSO Primary Target: DAT Primary Target Ki: 1nM
Size
10mg
Concentration
n/a
Applications
n/a
Other Names
GBR 12909 Dihydrochloride (1-(2-Bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine Hydrochloride, Dopamine Active Transporter Inhibitor, GBR 12909, DAT Inhibitor, GBR 12909, GBR12909)