Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (LFNG)
Description
Purity > 90% as determined by SDS-PAGE. MW: 55.2kDa. Full Length of Isoform 2: 1-250aa. N-terminal GST-tagged. Homo sapiens (Human). Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning