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Description
COX15 Monoclonal Antibody (2D2). Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is
Immunogen
n/a
Other Names
CEMCOX2, COX15 homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15