Affinity matured murine monoclonal antibody producing cell lines can be rapidly generated using repetitive, multiple site immunization strategy designated RIMMS. RIMMS capitalizes on rapid hypermutation and affinity maturation events which occur in B cell populations localized within secondary lymphatic tissue early in response to antigenic challenges. Along with using less antigen, this approach allows the investigator to obtain hybridomas rapidly.More information, please visit the website: http://www.creative-diagnostics.com/RIMMS-Services.html